Safety l Fluoridation Facts 71 66. Phipps KR, Orwoll ES, Mason JD, Cauley JA. Community water fluoridation, bone mineral density, and fractures: prospective study of effects in older women. BMJ 2000 7 321(7265):860-4. Abstract at: https://www.ncbi. nlm.nih.gov/pubmed/11021862. Article at: https://www.ncbi.nlm.nih. gov/pmc/articles/PMC27493. Accessed August 18, 2017. 67. Iida H, Kumar JV. The association between enamel fluorosis and dental caries in U.S. schoolchildren. J Am Dent Assoc 2009 140(7):855-62. Abstract at: https://www.ncbi.nlm.nih.gov/pubmed/19571049. Accessed August 28, 2017. 68. Massler M, Schour I. Chronology of crown and root development. In Massler M, Schour I (ed): Atlas of the Mouth in Health and Disease (2nd ed). Chicago: American Dental Association 1982. 69. Horowitz HS. Indexes for measuring dental fluorosis. J Public Health Dent 1986 46(4):179-83. Abstract at: https://www.ncbi.nlm.nih.gov/ pubmed/3465956. Accessed August 28, 2017. 70. Levertt D. Prevalence of dental fluorosis in fluoridated and nonfluoridated communities – a preliminary investigation. J Public Health Dent 1986 46(4):184-7. Abstract at: https://www.ncbi.nlm.nih.gov/ pubmed/3465957. Accessed August 28, 2017. 71. Pendrys DG, Katz RV, Morse DE. Risk factors for enamel fluorosis in a nonfluoridated population. Am J Epidemiol 1996 143(8):808-15. Abstract at: https://www.ncbi.nlm.nih.gov/pubmed/8610691. Accessed August 28, 2017. 72. Pendrys DG, Stamm JW. Relationship of total fluoride intake to beneficial effects and enamel fluorosis. J Dent Res 1990 69(Spec No):529-38. Abstract at: https://www.ncbi.nlm.nih.gov/pubmed/2179311. Accessed August 28, 2017. 73. Dean HT. The investigation of physiological effects by the epidemiological method. In: Moulton FR, ed. Fluorine and dental health. American Association for the Advancement of Science, Publication No. 19. Washington, DC 1942:23-31. 74. Kumar JV, Swango PA, Opima PN, Green EL. Dean’s fluorosis index: an assessment of examiner reliability. J Public Health Dent 2000 60(1):57- 9. Abstract at: https://www.ncbi.nlm.nih.gov/pubmed/10734619. Accessed August 28, 2017. 75. Beltrán-Aguilar ED, Barker L, Dye BA. Prevalence and severity of dental fluorosis in the United States, 1999-2004. NCHS data brief, no 53. Hyattsville, MD: National Center for Health Statistics. 2010. Abstract at: https://www. ncbi.nlm.nih.gov/pubmed/21211168. Available at: https://www.cdc.gov/ nchs/data/databriefs/db53.pdf. Accessed August 28, 2017. 76. Lewis DW, Banting DW. Water fluoridation: current effectiveness and dental fluorosis. Community Dent Oral Epidemiol 1994 22(3):153- 8. Abstract at: https://www.ncbi.nlm.nih.gov/pubmed/8070242. Accessed August 28, 2017. 77. Federal Register 1993 Dec 29 58(248):68826-68827. Available at: https://cdn.loc.gov/service/ll/fedreg/fr058/fr058248/fr058248.pdf. Accessed August 28, 2017. 78. Chankanka O, Levy SM, Warren JJ, Chalmers JM. A literature review of aesthetic perceptions of dental fluorosis and relationships with psychosocial aspects/oral health-related quality of life. Community Dent Oral Epidemiol 2010 38(2):97-109. Abstract at: https://www.ncbi.nlm. nih.gov/pubmed/20002631. Accessed August 28, 2017. 79. Do LG, Spencer A. Oral health-related quality of life of children by dental caries and fluorosis experience. J Public Health Dent 2007 67(3):132- 9. Abstract at: https://www.ncbi.nlm.nih.gov/pubmed/17899897. Accessed August 28, 2017. 80. Centers for Disease Control and Prevention. Surveillance for dental caries, dental sealants, tooth retention, edentulism, and enamel fluorosis - United States, 1988-1994 and 1999-2002. MMWR 2005:54(No. SS-3). Available at: https://www.cdc.gov/mmwr/indss_2005.html. Accessed August 28, 2017. 81. Dean HT. Endemic fluorosis and its relation to dental caries. Public Health Rep 1938 53(33):1443-52. Article at: https://www.jstor.org/ stable/4582632. Accessed August 28, 2017. 82. Dean HT, Arnold FA, Elvove E. Domestic water and dental caries: V. Additional studies of the relation of fluoride domestic waters to dental caries experience in 4,425 white children, aged 12 to 14 years, of 13 cities in 4 states. Public Health Rep 1942 57(32):1155-79. Article at: https:// www.jstor.org/stable/4584182. Accessed August 28, 2017. 83. Horowitz HS. Fluoride and enamel defects. Adv Dent Res 1989 3(2):143-6. Abstract at: https://www.ncbi.nlm.nih.gov/pubmed/2701157. Accessed August 28, 2017. 84. Berg J, Gerweck C, Hujoel PP, King R, Krol DM, Kumar J, Levy S, Pollick H, Whitford GM, Strock S, Aravamudhan K, Frantsve-Hawley J, Meyer DM. American Dental Association Council on Scientific Affairs Expert Panel on Fluoride Intake From Infant Formula and Fluorosis. Evidence-based clinical recommendations regarding fluoride intake from reconstituted infant formula and enamel fluorosis: a report of the American Dental Association Council on Scientific Affairs. J Am Dent Assoc 2011 142(1):79-87. Abstract at: https://www.ncbi.nlm.nih.gov/pubmed/21243832. Accessed August 23, 2017. 85. Centers for Disease Control and Prevention. Overview: infant formula. Available at: https://www.cdc.gov/fluoridation/faqs/infant-formula. html. Accessed August 23, 2017. 86. U.S. Department of Health and Human Services. HHS: Proposed guidelines on fluoride in drinking water. 2011 Mar 8. Available at: https://www. medscape.com/viewarticle/738322. Accessed August 23, 2017. 87. American Public Health Association. Policy Statement Data Base. Policy 20087. Community water fluoridation in the United States. 2008 Oct 28. Available at: https://www.apha.org/policies-and-advocacy/public- health-policy-statements. Accessed August 23, 2017. 88. New York State Department of Health. Guidance for use of fluoridated water for feeding during infancy. Available at: http://www.health.ny.gov/ prevention/dental/fluoride_guidance_during_infancy.htm. Accessed: August 23, 2017. 89. Celeste RK, Luz PB. Independent and additive effects of different sources of fluoride and dental fluorosis. Pediatr Dent 2016 38(3):233-8. Abstract at: https://www.ncbi.nlm.nih.gov/pubmed/27306248. Accessed August 23, 2017. 90. Pendrys DG. Risk of enamel fluorosis in nonfluoridated and optimally fluoridated populations: considerations for the dental professional. J Am Dent Assoc 2000 131(6):746-55. Abstract at: https://www.ncbi.nlm.nih. gov/pubmed/10860326. Accessed August 23, 2017. 91. Ismail AI, Hasson H. Fluoride supplements, dental caries and fluorosis: a systematic review. J Am Dent Assoc 2008 139(11):1457-68. Abstract at: https://www.ncbi.nlm.nih.gov/pubmed/18978383. Accessed October 2, 2017. 92. American Dental Association. Oral health topics. Caries risk assessment and management. Available at: http://www.ADA.org/en/member-center/ oral-health-topics/caries-risk-assessment-and-management. Accessed October 2, 2017. 93. American Dental Association. Oral Health Topics. Mouthwash (mouthrinse). Available at: http://www.ADA.org/en/member-center/oral-health- topics/mouthrinse. Accessed October 2, 2017. 94. 21 CFR 330.1 General conditions for general recognition as safe, effective and not misbranded. Available at: https://www.ecfr.gov/cgi-bin/text-idx? SID=9b3e9844e3dadeee276f8c08d75bca82&mc=true&node=se21.5. 330_11&rgn=div8. Accessed October 27, 2017. 95. 21 CFR 330.5 Drug categories. Available at: https://www.ecfr.gov/cgi- bin/retrieveECFR?gp=&SID=9b3e9844e3dadeee276f8c08d75bca82 &mc=true&n=pt21.5.330&r=PART&ty=HTML#se21.5.330_5. Accessed October 27, 2017. 96. 21 CFR 355.50 Labeling of anticaries drug products. Available at: https:// www.ecfr.gov/cgi-bin/text-idx?SID=ec4da50b801ce671286ff761c73 0113f&mc=true&node=se21.5.355_150&rgn=div8. Accessed October 27, 2017. 97. Whitford GM. Acute toxicity of ingested fluoride. In Buzalaf MAR (ed): Fluoride and the Oral Environment. Monogr Oral Sci. Basel, Karger. 2011 22:66-80. Abstract at: https://www.ncbi.nlm.nih.gov/ pubmed/21701192. Accessed October 2, 2017. 98. Stevenson CA, Watson AR. Fluoride osteosclerosis. American Journal of Roetgenology, Radium Therapy and Nuclear Medicine 1957 78(1):13-18. 99. Hodge HC. The safety of fluoride tablets or drops. In: Continuing evaluation of the use of fluorides. Johansen E, Tavaes DR, Olsen TO, eds. Boulder, Colorado Westview Press:1979:253-75. 100. U.S. Environmental Protection Agency. Superfund: national priorities list (NPL). Available at: https://www.epa.gov/superfund/superfund- national-priorities-list-npl. Accessed August 16, 2017.