Dental Drug and Medical
Conditions Kit
Kit includes:
• ADA Dental Drug Handbook, Second Edition
• The ADA Practical Guide to Patients with Medical Conditions
(see p. 25 for description)
K027 Kit, 2 books
Members $104.95 Retail $152.95
Be prepared for
patients with a range
of medical conditions!
30
Chapter 2 l Antibiotics
Penicillin. VK. (a. penicillin)
Tablet:. 250. mg,. 500. mg
Liquid:. 125. mg/5. mL,. 250. mg/5. mL.
ORAL CONDITIONS
• Acute oral infection
SAMPLE PRESCRIPTION
• Take 1 tablet (500 mg) 4 times per day for 5–7 days (20–28 tablets)
CONTRAINDICATIONS
• Penicillin allergies, including anaphylaxis
• Asthmatic patients prone to allergy
CAUTIONS
• Cephalosporins, carbapenem, imipenem hypersensitivity
• History of antibiotic-associated colitis
MAJOR &SEVERE
DRUG INTERACTIONS
• This drug decreases the effect of live vaccines such as BCG, cholera, typhoid
• This drug increases the concentration of methotrexate
• This drug increases the effect of warfarin
• The following medications may decrease the therapeutic effects of this drug:
-Tetracycline such as minocycline, doxycycline, demeclocycline
-Proton-pump inhibitors such as esomeprazole, lansoprazole,
dexilansoprazole, omeprazole, pantoprazole
-GLP-1 receptor agonist antidiabetic medications such as exenatide and
lixisenatide
• Aminoglycosides such as amikacin, gentamicin, streptomycin, tobramycin
increases the concentration, efficacy and bactericidal effects of this drug
ADVERSE DRUG REACTIONS
Common reactions:
• Nausea, vomiting, diarrhea,
epigastric discomfort
• Candidiasis and other fungal
infections black, hairy tongue
Less-common reactions:
• C. difficile-associated diarrhea
• Anemia, positive Coombs reaction,
bleeding
• Interstitial nephritis
• Hypersensitivity reaction
PATIENT
CONSIDERATIONS
• Pregnancy Category B (fetal risk cannot be ruled out)
• Lactation: excreted in breast milk infant risk cannot be ruled out
• No renal or hepatic dose adjustment needed, however, monitor patients
with renal impairment
• Take on an empty stomach
DRUG CONSIDERATIONS
• Bioavailability: 25%
• Peak serum time: 0.5–1 hour
• Protein-binding: 80%
• Half-life: 0.5 hour
• Excretion: urine
121
Section 2 l Pediatric Drug Management
3a l Odontogenic Infection Management
Antibiotics are not indicated if the child is afebrile or no facial swelling is present.
Signs of systemic involvement such as fever or facial cellulitis warrant emergency
and administration of an oral antibiotic for 5 to 7 days. If the facial
swelling is encroaching into the orbital space or the airway, then referral for medical
management, including intravenous antibiotics, may be indicated.
3. for Odontogenic Infections in Pediatric Patients*
Antibiotic Sample Dosage Forms Comments
40kg:
20–40. mg/kg/day.
divided. every. 8. hours
OR.
25–45. mg/kg/day.
.every. 12. hours
40kg:
250–500. mg. every. .
.hours
OR.
500–875. mg. every. .
12. hours
Suspension:
125. mg/5. mL,. .
250. mg/5. mL,. .
400. mg/5. mL
Chewable Tablet:
125. mg,. 250. mg.
Tablet/Capsule:
250. mg,. 500. mg,. .
875. mg.
Drug. of. choice.
for. odontogenic.
infections
Clavulanic Acid
(Augmentin)**
40kg:
25–45. mg/kg/day.
divided. every. 12. hours
40kg:
.mg. every. .
12. hours
Suspension:
125. mg/31. 25. mg/5. mL,.
250. mg/62. 5. mg/5. mL,.
400. mg/57. mg/5. mL
Chewable Tablet:
200. mg/28. 5. mg,. .
400. mg/57. mg.
Tablet/Capsule:
250. mg/125. mg,. .
500. mg/125. mg,. .
875. mg/125. mg
Drug. of. choice.
for. odontogenic.
infections. with.
anaerobic. bacterial.
involvement
Azithromycin 16 years:
5–12. mg/kg. once. a. day.
(maximum. 500. mg/day)
16 years:
250–600. mg. once. a. day
Suspension:
100. mg/5. mL,. .
200. mg/5. mL,.
Tablet/Capsule:
250. mg,. 500. mg
Alternative. for. type. I.
allergy. to. penicillins/
cephalosporins
Clindamycin Children:
8–20. mg/kg/day.
divided. every. 8. hours. as.
hydrochloride. salt
OR
8–25. mg/kg/day.
divided. every. 8. hours. as.
palmitate. salt
Suspension:
75. mg/5. mL
Tablet/Capsule:
150. mg,. 300. mg
Alternative. for. type. I.
allergy. to. penicillins/
cephalosporins
Effective. for.
infections. with. .
gram-positive. aerobic.
bacteria. and. .
gram-positive. or.
gram-negative.
anaerobic. bacteria
*NOTE: The sample prescriptions in this handbook represent a general recommendation. Clinicians are
responsible to adjust the prescription dose, frequency, and length of treatment based on the procedure
performed, the medicine prescribed, and the patient conditions such as age, weight, metabolism, and
liver and renal
function. INCLUDES
**Dosage Based on Amoxicillin Component.
B E S T S E L L E R
ADA Dental Drug Handbook: A Quick Reference,
Second Edition
The second edition of the ADA Dental Drug Handbook includes the
latest, most up-to-date information to assist in treating your patients.
The book presents information on commonly encountered drugs in
the dental office in an easy-to-follow format, making it a go-to drug
reference for dental professionals.
J05921BT Spiral-bound book +e-book, 190 pages
Members $44.95 Retail $64.95
Book ISBN: 978-1-68447-160-7 |e-book ISBN: 978-1-68447-161-4
• Information about drugs used in dentistry, such as
analgesics, antibiotics, antifungals, antivirals, anxiolytics,
fluorides, local anesthetics and corticosteroids
• Sample prescriptions with dosage, frequency
and route of administration
• Detailed, full-color drug monographs with black box
warnings, cautions and contraindications, potential
adverse reactions, possible drug interactions and more
• Smoking cessation, salivary management and
oral lesion treatments
• OTC products with the ADA Seal of Acceptance
• ADA Guidelines on procedures such as general
anesthesia, antibiotic prophylaxis and medication-
related osteonecrosis of the jaw
• Drug management for
-pediatrics
-emergency situations
-special care conditions such as
hypertension and pregnancy
Trust the ADA Dental
Drug Handbook: A Quick
Reference, Second Edition
for contraindications and
safe prescribing practices.
"Very well illustrated and easy to navigate through.”
-Dr. Walid Harsha, Yakima, WA
ORDER ONLINE: ADASTORE.ORG ORDER BY PHONE: 800.947.4746 21 20
CLINICAL
RESOURCES
P
R
A
C
T
I
C
E
M
A
N
A
G
E
M
E
N T
Conditions Kit
Kit includes:
• ADA Dental Drug Handbook, Second Edition
• The ADA Practical Guide to Patients with Medical Conditions
(see p. 25 for description)
K027 Kit, 2 books
Members $104.95 Retail $152.95
Be prepared for
patients with a range
of medical conditions!
30
Chapter 2 l Antibiotics
Penicillin. VK. (a. penicillin)
Tablet:. 250. mg,. 500. mg
Liquid:. 125. mg/5. mL,. 250. mg/5. mL.
ORAL CONDITIONS
• Acute oral infection
SAMPLE PRESCRIPTION
• Take 1 tablet (500 mg) 4 times per day for 5–7 days (20–28 tablets)
CONTRAINDICATIONS
• Penicillin allergies, including anaphylaxis
• Asthmatic patients prone to allergy
CAUTIONS
• Cephalosporins, carbapenem, imipenem hypersensitivity
• History of antibiotic-associated colitis
MAJOR &SEVERE
DRUG INTERACTIONS
• This drug decreases the effect of live vaccines such as BCG, cholera, typhoid
• This drug increases the concentration of methotrexate
• This drug increases the effect of warfarin
• The following medications may decrease the therapeutic effects of this drug:
-Tetracycline such as minocycline, doxycycline, demeclocycline
-Proton-pump inhibitors such as esomeprazole, lansoprazole,
dexilansoprazole, omeprazole, pantoprazole
-GLP-1 receptor agonist antidiabetic medications such as exenatide and
lixisenatide
• Aminoglycosides such as amikacin, gentamicin, streptomycin, tobramycin
increases the concentration, efficacy and bactericidal effects of this drug
ADVERSE DRUG REACTIONS
Common reactions:
• Nausea, vomiting, diarrhea,
epigastric discomfort
• Candidiasis and other fungal
infections black, hairy tongue
Less-common reactions:
• C. difficile-associated diarrhea
• Anemia, positive Coombs reaction,
bleeding
• Interstitial nephritis
• Hypersensitivity reaction
PATIENT
CONSIDERATIONS
• Pregnancy Category B (fetal risk cannot be ruled out)
• Lactation: excreted in breast milk infant risk cannot be ruled out
• No renal or hepatic dose adjustment needed, however, monitor patients
with renal impairment
• Take on an empty stomach
DRUG CONSIDERATIONS
• Bioavailability: 25%
• Peak serum time: 0.5–1 hour
• Protein-binding: 80%
• Half-life: 0.5 hour
• Excretion: urine
121
Section 2 l Pediatric Drug Management
3a l Odontogenic Infection Management
Antibiotics are not indicated if the child is afebrile or no facial swelling is present.
Signs of systemic involvement such as fever or facial cellulitis warrant emergency
and administration of an oral antibiotic for 5 to 7 days. If the facial
swelling is encroaching into the orbital space or the airway, then referral for medical
management, including intravenous antibiotics, may be indicated.
3. for Odontogenic Infections in Pediatric Patients*
Antibiotic Sample Dosage Forms Comments
40kg:
20–40. mg/kg/day.
divided. every. 8. hours
OR.
25–45. mg/kg/day.
.every. 12. hours
40kg:
250–500. mg. every. .
.hours
OR.
500–875. mg. every. .
12. hours
Suspension:
125. mg/5. mL,. .
250. mg/5. mL,. .
400. mg/5. mL
Chewable Tablet:
125. mg,. 250. mg.
Tablet/Capsule:
250. mg,. 500. mg,. .
875. mg.
Drug. of. choice.
for. odontogenic.
infections
Clavulanic Acid
(Augmentin)**
40kg:
25–45. mg/kg/day.
divided. every. 12. hours
40kg:
.mg. every. .
12. hours
Suspension:
125. mg/31. 25. mg/5. mL,.
250. mg/62. 5. mg/5. mL,.
400. mg/57. mg/5. mL
Chewable Tablet:
200. mg/28. 5. mg,. .
400. mg/57. mg.
Tablet/Capsule:
250. mg/125. mg,. .
500. mg/125. mg,. .
875. mg/125. mg
Drug. of. choice.
for. odontogenic.
infections. with.
anaerobic. bacterial.
involvement
Azithromycin 16 years:
5–12. mg/kg. once. a. day.
(maximum. 500. mg/day)
16 years:
250–600. mg. once. a. day
Suspension:
100. mg/5. mL,. .
200. mg/5. mL,.
Tablet/Capsule:
250. mg,. 500. mg
Alternative. for. type. I.
allergy. to. penicillins/
cephalosporins
Clindamycin Children:
8–20. mg/kg/day.
divided. every. 8. hours. as.
hydrochloride. salt
OR
8–25. mg/kg/day.
divided. every. 8. hours. as.
palmitate. salt
Suspension:
75. mg/5. mL
Tablet/Capsule:
150. mg,. 300. mg
Alternative. for. type. I.
allergy. to. penicillins/
cephalosporins
Effective. for.
infections. with. .
gram-positive. aerobic.
bacteria. and. .
gram-positive. or.
gram-negative.
anaerobic. bacteria
*NOTE: The sample prescriptions in this handbook represent a general recommendation. Clinicians are
responsible to adjust the prescription dose, frequency, and length of treatment based on the procedure
performed, the medicine prescribed, and the patient conditions such as age, weight, metabolism, and
liver and renal
function. INCLUDES
**Dosage Based on Amoxicillin Component.
B E S T S E L L E R
ADA Dental Drug Handbook: A Quick Reference,
Second Edition
The second edition of the ADA Dental Drug Handbook includes the
latest, most up-to-date information to assist in treating your patients.
The book presents information on commonly encountered drugs in
the dental office in an easy-to-follow format, making it a go-to drug
reference for dental professionals.
J05921BT Spiral-bound book +e-book, 190 pages
Members $44.95 Retail $64.95
Book ISBN: 978-1-68447-160-7 |e-book ISBN: 978-1-68447-161-4
• Information about drugs used in dentistry, such as
analgesics, antibiotics, antifungals, antivirals, anxiolytics,
fluorides, local anesthetics and corticosteroids
• Sample prescriptions with dosage, frequency
and route of administration
• Detailed, full-color drug monographs with black box
warnings, cautions and contraindications, potential
adverse reactions, possible drug interactions and more
• Smoking cessation, salivary management and
oral lesion treatments
• OTC products with the ADA Seal of Acceptance
• ADA Guidelines on procedures such as general
anesthesia, antibiotic prophylaxis and medication-
related osteonecrosis of the jaw
• Drug management for
-pediatrics
-emergency situations
-special care conditions such as
hypertension and pregnancy
Trust the ADA Dental
Drug Handbook: A Quick
Reference, Second Edition
for contraindications and
safe prescribing practices.
"Very well illustrated and easy to navigate through.”
-Dr. Walid Harsha, Yakima, WA
ORDER ONLINE: ADASTORE.ORG ORDER BY PHONE: 800.947.4746 21 20
CLINICAL
RESOURCES
P
R
A
C
T
I
C
E
M
A
N
A
G
E
M
E
N T
